OPTIMIZE trial: long term azithromycin preserves lung function in CF children
By Michael Woodhead
31 Jul 2018
The longest randomised controlled trial of azithromycin treatment in children with cystic fibrosis has shown a 44% reduction in exacerbations over 18 months. The OPTIMIZE trial conducted in 221 US children with CF aged 6 months-18 years with recent Pseudomanas aeruginosa acquisition also found that regular treatment with oral azithromycin appears safe when the macrolide ...