Cystic Fibrosis

OPTIMIZE trial: long term azithromycin preserves lung function in CF children

The longest randomised controlled trial of azithromycin treatment in children with cystic fibrosis has shown a 44% reduction in exacerbations over 18 months. The OPTIMIZE trial conducted in 221 US children with CF aged 6 months-18 years with recent Pseudomanas aeruginosa acquisition also found that regular treatment with oral azithromycin appears safe when the macrolide ...

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