Rare diseases

The challenge of GCA diagnosis: why history and examination are still important

In patients with suspected giant cell arteritis (GCA), there is no single clinical or laboratory feature likely to shift pretest probability sufficiently that further confirmatory testing is not required, a new study has shown. A systematic review and meta-analysis of the evidence, comprising 68 studies and over 14,000 patients, estimated likelihood ratios (LR) for the ...

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