rheumatology
Rheumatoid arthritis

Initial methotrexate dose makes no difference to outcomes: study

There appears to be no benefit from starting newly diagnosed patients with rheumatoid arthritis on high dose methotrexate (≥15mg/week) compared to low dose (≤10mg/week) as either monotherapy or in combination with other agents. This is despite evidence that initiating doses appear to have increased over time, according to a study of DMARD-naïve patients from the ...

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