There appears to be no benefit from starting newly diagnosed patients with rheumatoid arthritis on high dose methotrexate (≥15mg/week) compared to low dose (≤10mg/week) as either monotherapy or in combination with other agents. This is despite evidence that initiating doses appear to have increased over time, according to a study of DMARD-naïve patients from the ...
Initial methotrexate dose makes no difference to outcomes: study
By Mardi Chapman
6 Dec 2017