Psoriatic arthritis

Guselkumab inhibition of the IL-23 p19 subunit effective in PsA

The IL-23 inhibitor guselkumab has been shown to be effective in psoriatic arthritis patients including those who are biologic-naive or been previously treated with one or two anti-TNFs. The DISCOVER trials, published in The Lancet, showed treatment with guselkumab improved the primary outcome of ACR20 and a number of secondary outcomes including skin and joint ...

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