Antidepressant not backed for fibromyalgia

Any potential benefits of the antidepressant mirtazapine in fibromyalgia are outweighed by its potential harms, a Cochrane review concludes. The review of three studies involving 606 participants comparing mirtazapine with placebo showed no benefit of mirtazapine over placebo for pain relief of 50% or greater, Patient Global Impression of Change, improvement of HRQoL of 20% ...

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