Adalimumab effective in JIA uveitis, but safety concerns exist

Adalimumab in combination with methotrexate is an effective treatment for children with JIA associated uveitis, a study in this week’s NEJM reports. The randomised placebo controlled SYCAMORE trial involving 90 children and adolescents with JIA and active uveitis was stopped early because of a strong beneficial effect in the treatment arm. Overall, at two-year follow ...

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