Targeted thermal vapour ablation of severely emphysematous lung tissue improves lung function and quality of life with an acceptable safety profile, 12 month results of the joint Australian-European STEP-UP study confirm.
As reported by the limbic, six-month results from the study of 70 patients with severe, upper lobe-prominent emphysema who were randomised the ablation or usual care found FEV1 had improved by 14.7% and St George’s Respiratory Questionnaire Scores had improved by 9.7 points in the ablation group (changes of 12% and 8 points, respectively, are considered clinically meaningful).
At the time Professor Greg Snell, from the Alfred Hospital in Melbourne, who contributed to STEP-UP said: “Although the trial had specific, tight selection criteria, the findings would apply to many Australian emphysema patients with patterns of disease not easily treated by any other means.”
“In addition, it may be possible to repeat treatments, but further trials will help clarify this,” he told the limbic.
“It’s reasonable to imagine more widespread use of such technology with the aim of improving quality of life and eventually – we hope – length of life.”