Targeting viral infections before asthma

Prostaglandin D2 (PGD2) antagonists may be useful antivirals for the treatment of viral bronchiolitis and possibly as primary preventatives for asthma. Queensland-led research has shown that respiratory syncytial virus (RSV) infection up-regulates hematopoietic prostaglandin D synthase expression resulting in PGD2 release by airway epithelial cells. They also found PGD2 production was elevated in nasopharyngeal samples ...

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