Prostaglandin D2 (PGD2) antagonists may be useful antivirals for the treatment of viral bronchiolitis and possibly as primary preventatives for asthma. Queensland-led research has shown that respiratory syncytial virus (RSV) infection up-regulates hematopoietic prostaglandin D synthase expression resulting in PGD2 release by airway epithelial cells. They also found PGD2 production was elevated in nasopharyngeal samples ...
Targeting viral infections before asthma
By Mardi Chapman
17 May 2018