It’s time for a pivot to a healthier diet for patients with cystic fibrosis: away from the legacy high fat/high energy CF diet which may have adverse health consequences as people with CF age and in the era of effective CFTR modulator therapies.
Ms Tamarah Katz, a paediatric respiratory dietician at the Sydney Children’s Hospital, told the TSANZSRS 2024 meeting that in the past the importance of nutrition for patients with CF trumped the importance of a healthy diet.
However the evidence from a 2018 study [link here] was that children with CF were receiving 44% of their energy intake from junk food, mirroring an increase in overweight and obesity in the CF population.
Ms Katz said there was a need to consider not just the impact of nutrition on the underlying CF but on the patient’s future risk of cardiovascular disease and cancer, particularly colorectal cancer (CRC) which was already increased in people with CF.
She said the Dietary Approaches to Stop Hypertension (DASH) diet had been shown to reduce the risk of CVD in an otherwise healthy population by about 20%.
DASH dietary patterns focus on fruit, vegetables, whole grains, nuts, seeds, legumes and lean meat such as fish and chicken. Dairy foods, either low or full fat, were also included but butter should be limited. Monounsaturated fatty acids from sources such as walnuts, avocado, and olive oil, and polyunsaturated fatty acids from canola oil were included.
DASH also recommended reducing salt intake which Ms Katz said was probably twice as high as required in an average Australian diet.
Ms Katz said the DASH diet was also one of a few dietary patterns shown to be inversely associated with CRC risk [link here]
She said there was convincing evidence that alcohol, processed meat and body fatness were associated with increased risk of CRC and probable evidence of an association with red meat.