respiratory
Infectious diseases

Gene sequencing gives early warning on drug resistance in TB


Computer simulation of 3D protein structures associated with gene mutations in Mycobacterium tuberculosis has been used to predict resistance to pyrazinamide in tuberculosis treatment. The technology can be used to ‘pre-emptively identify likely resistance mutations in drug targets’ rather than waiting to see if a patient fails lengthy therapy. Researchers from the Doherty Institute and ...

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