Cystic Fibrosis

CFTR modulation improves bacterial clearance

Addressing CFTR dysfunction improves overall bacterial clearance from sputum, according to research presented here at ECSF 2015. The study looked at the short and long term effects of ivacaftor on the sputum microbiota of 12 adult patients with at least one copy of the G551D CFTR mutation, eight of whom were culture positive for P. aeruginosa ...

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