Pertussis prevention in older Australians with COPD or asthma needs a boost through increased community awareness and vaccination programs, according to new data.
A study, published in Emerging Infectious Diseases [link here], comprised an analysis of 992 patients ≥50 years of age with a clinical diagnosis of pertussis recorded in the IQVIA GP EMR database between 2015 and 2019.
The study found pertussis incidence rates decreased from 91.4 per 100,000 persons in 2015 to 57.6 per 100,000 in 2019.
Incidence rates (IRs) were consistently higher in women than men (110.5 v 74.5 per 100,000 persons) and highest in 50–64 year-olds compared to 65-74, 75-84 and ≥85 year-olds.
Patients with COPD or asthma had higher incidence rates of pertussis compared with the overall population ≥50 years of age.
On multivariate analysis, concurrent asthma conferred an adjusted overall risk (aOR) for pertussis of 2.94 and COPD 1.88.
A prior prescription of antibiotics for cough was also an important predictor of pertussis in older Australians (aOR 7.00) while a history of influenza vaccination reduce the risk of pertussis (aOR 0.38).