respiratory
Cystic Fibrosis

Benefits of cystic fibrosis combination therapies maintained in the long-term: trials

Treatment with lumacaftor-ivacaftor (Orkambi) was tolerated well and maintained its efficacy in children aged 6-11 years out to 120 weeks, according to long-term trial data. Previous trials have demonstrated success with the combination therapy in children homozygous for the F508del-CFTR mutation out to 24 weeks. “The safety and efficacy of the lumacaftor-ivacaftor combination has not ...

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