A continuous infusion of antibiotics is no better than intermittent infusion in improving the outcomes of critically ill patients with sepsis, an Australian study finds.
The study of 432 patients from 25 ICUs across Australia found no difference in ICU-free days or 90-day survival between patients randomised to continuous or 30-minute infusions of β-lactam antibiotics.
The study led by Joel Dulhunty from the Royal Brisbane and Women’s Hospital was published in the American Journal of Respiratory and Critical Care Medicine.