Australia needs post-COVID respiratory rehab model: Prof Peter Wark
A new model of care is urgently needed for follow up of survivors of COVID-19 who had severe acute disease requiring breathing support, a leading respiratory physician says. Professor Peter Wark, of the John Hunter Hospital in Newcastle, says the COVID-19 pandemic has meant that a large number of Australians have...
Respiratory physician reveals lessons learnt from Post-COVID Clinic
Reassuring patients they’re not going to be “permanently damaged” is a key part of managing long-COVID, the Australian respiratory physician leading a specialised clinic for the condition says. Associate Professor Lou Irving was the driving force behind the Royal Melbourne Hospital’s Post-Covid Clinic when it opened a little over two years...
Croup prevention: do pregnancy supplements have a role?
The risk of croup in infants may be reduced by maternal consumption of fish oil and vitamin D during pregnancy, evidence from a European randomised controlled trial has shown. Findings presented at the European Respiratory Society International Congress in Barcelona (ERS 2022), showed that the risk of croup before the...
Australia needs post-COVID respiratory rehab model: Prof Peter Wark
A new model of care is urgently needed for follow up of survivors of COVID-19 who had severe acute disease requiring breathing support, a leading respiratory physician says. Professor Peter Wark, of the John Hunter Hospital in Newcastle, says the COVID-19...
A new model of care is urgently needed for follow up of survivors of COVID-19 who had severe acute disease...
Respiratory physician reveals lessons learnt from Post-COVID Clinic
Reassuring patients they’re not going to be “permanently damaged” is a key part of managing long-COVID, the Australian respiratory physician leading a specialised clinic for the condition says. Associate Professor Lou Irving was the driving force behind the Royal Melbourne Hospital’s...
Reassuring patients they’re not going to be “permanently damaged” is a key part of managing long-COVID, the Australian respiratory physician...
Croup prevention: do pregnancy supplements have a role?
The risk of croup in infants may be reduced by maternal consumption of fish oil and vitamin D during pregnancy, evidence from a European randomised controlled trial has shown. Findings presented at the European Respiratory Society International Congress in Barcelona (...
The risk of croup in infants may be reduced by maternal consumption of fish oil and vitamin D during pregnancy,...
COVID-19: hospital ‘successfully’ covering ICU with ward-based CPAP
Patients with COVID-19 respiratory failure can be managed with CPAP on a standard medical ward without any increase in mortality compared to placing them in ICU, an Australian hospital team have reported. The message is based on an observational study during...
Patients with COVID-19 respiratory failure can be managed with CPAP on a standard medical ward without any increase in mortality...
Long COVID partly inflammation driven: PHOSP-COVID
Systemic inflammation, and obesity, might be treatable traits in patients with long COVID and could potentially underpin a precision medicine approach to managing the condition, UK researchers say. The study, published in The Lancet Respiratory Medicine, also revealed...
Systemic inflammation, and obesity, might be treatable traits in patients with long COVID and could potentially underpin a precision...
Top research priorities for long-term respiratory effects of COVID-19
The top research priorities for understanding the long-term effects of COVID-19 in the context of airways disease have been outlined by respiratory experts. The UK PHOSP-COVID consortium, which included several respiratory physicians and scientists, invited over 200 experts to submit...
The top research priorities for understanding the long-term effects of COVID-19 in the context of airways disease have been outlined...
Updated local advice on respiratory therapies during COVID-19
The Australasian Sleep Association has updated its consensus statement on the safe use of respiratory therapy and NIV to minimise aerosolisation of COVID-19. The statement acknowledges both the relatively low rates of...
The Australasian Sleep Association has updated its consensus statement on the...
RECOVERY trial investigators warned against including dexamethasone at start
The researchers leading the RECOVERY trial were told by many people they should not have included dexamethasone in the study when it launched at the start of the first wave of COVID-19, delegates at the British Thoracic Society Winter meeting...
The researchers leading the RECOVERY trial were told by many people they should not have included dexamethasone in the study...
Double-lung transplant from donor with previous COVID-19 performed successfully
A double-lung transplantation was carried out successfully from a donor who had previously been infected with the coronavirus, according to a case report from Belgium. The transplantation was completed without viral transmission to the...
A double-lung transplantation was carried out successfully from a donor who had previously been infected with the coronavirus, according...
Inhaled corticosteroids trialled for COVID-19
A trial known as PRINCIPLE has begun investigating the inhaled corticosteroid budesonide as a treatment for COVID-19 in the UK. The Platform Randomised trial of Interventions against COVID-19 in older peoPLE (PRINCIPLE) has recruited...
A trial known as PRINCIPLE has begun investigating the inhaled corticosteroid budesonide as a...
First guidelines for respiratory illness in children with cerebral palsy
Australian clinicians have led international efforts to develop the first clinical care recommendations for preventing and managing respiratory illness in children with cerebral palsy (CP). The consensus statement developed by respiratory specialists at the Perth Children’s Hospital is aimed at tackling...
Australian clinicians have led international efforts to develop the first clinical care recommendations for preventing and managing respiratory illness in...
NTM to blame for outbreak of ‘hot tub lung’
Respiratory specialists in Queensland say vigilance is needed for ‘hot tub lung’ following a cluster of five cases in family members secondary to aerosolised non‐tuberculous mycobacteria (NTM) from an indoor swimming pool. The diagnosis of NTM proved to be a challenge,...
Respiratory specialists in Queensland say vigilance is needed for ‘hot tub lung’ following a cluster of five cases in family...
Big decrease in bronchiolitis admissions seen in pandemic
The lockdowns and handwashing policies introduced to curb COVID-19 have had the unexpected spin-off of a huge decrease in hospital admissions for paediatric acute respiratory illness, NSW figures show. Rates of paediatric emergency department attendances, RSV positive tests and admissions for...
The lockdowns and handwashing policies introduced to curb COVID-19 have had the unexpected spin-off of a huge decrease in hospital...
Macrolide anti-inflammatory effects to be investigated in early COVID-19 disease
A macrolide widely used in severe SARS-CoV and MERS-CoV is being trialled by UK respiratory experts as a potential treatment for patients with moderately severe COVID-19. The multicentre phase II/III ATOMIC2 trial will compare azithromycin...
A macrolide widely used in severe SARS-CoV and MERS-CoV is being trialled by UK respiratory experts as a potential treatment...
Early rehabilitation advised after COVID-19 disease
People hospitalised with severe COVID-19 should receive early bedside rehabilitation, be assessed for oxygen requirements prior to discharge and receive a comprehensive assessment of their rehabilitation needs 6 to 8 weeks after discharge, an international task force recommends. Professor Anne...
People hospitalised with severe COVID-19 should receive early bedside rehabilitation, be assessed for oxygen requirements prior to discharge and receive...
Pulmonary aspergillosis associated with COVID-19
Critically ill patients with COVID-19 who are not recovering as expected should be screened for pulmonary aspergillosis, UK experts advise. A group of infectious disease specialists, haematologists and respiratory specialists from institutions across London have said fungal disease consistent with invasive...
Critically ill patients with COVID-19 who are not recovering as expected should be screened for pulmonary aspergillosis, UK experts advise. A...
Pulmonary complications and mortality high in surgical patients with COVID-19
High rates of respiratory complications suggest that thresholds for surgery should be higher than usual for patients during the COVID-19 pandemic - and especially for older aged men, researchers say. A study published in The Lancet found postoperative pulmonary complications...
High rates of respiratory complications suggest that thresholds for surgery should be higher than usual for patients during the COVID-19...
No need to ‘reinvent the wheel’ on post-COVID rehab programs, say clinicians
Building on existing well-established pulmonary rehabilitation services is likely the best approach for supporting patients with COVID-19 after they are discharged from hospital, a UK cross-specialty survey of clinicians has found. Responses from more than 1,000 consultants, physiotherapists, dieticians and other...
Building on existing well-established pulmonary rehabilitation services is likely the best approach for supporting patients with COVID-19 after they are...
COVID-19 patients need physio support for respiratory recovery
Patients recovering from COVID-19 should be targeted for physiotherapy interventions for respiratory management, exercise and mobilisation, according to new Australian guidelines for physiotherapy. The new guidelines aim to prevent complications of the respiratory system and muscle deconditioning, speed up recovery from mechanical...
Patients recovering from COVID-19 should be targeted for physiotherapy interventions for respiratory management, exercise and mobilisation, according to new Australian...
Prof Grant Waterer: Don’t panic in a pandemic; stick to EBM.
Clinicians have been urged to resist the urge to do “something” in severe COVID-19 disease and instead remember their Hippocratic oath to do no harm - and stick with evidence-based therapies. A Comment article in the AJRCCM, led by Professor...
Clinicians have been urged to resist the urge to do “something” in severe COVID-19 disease and instead remember their Hippocratic...
Lung ultrasound training made available for COVID-19
Free online training in the use of lung ultrasound to diagnose COVID-19 is being made available to upskill medical, nursing and paramedical staff. Hosted by the University of Melbourne, the training takes about 30 hours and includes simulation exercises. Participants...
Free online training in the use of lung ultrasound to diagnose COVID-19 is being made available to upskill medical, nursing...
COVID-19 patients often infected with other respiratory viruses
About 1 in 5 people with COVID-19 are also infected with other respiratory viruses, according to a preliminary analysis. The authors from Stanford School of Medicine say their findings challenge the assumption that if a patient tests...
About 1 in 5 people with COVID-19 are also infected with other respiratory viruses, according to a preliminary...
Promise with new triple drug combo for resistant TB
A new triple therapy for extensively drug-resistant (XDR) tuberculosis and complicated forms of multidrug-resistant (MDR) tuberculosis may replace the multi-drug regimens currently in use and offers some promise in the race to meet WHO End...
A new triple therapy for extensively drug-resistant (XDR) tuberculosis and complicated forms of multidrug-resistant (MDR) tuberculosis...
Coronavirus may be no worse than seasonal flu: respiratory physician
The outbreak of the 2019 novel coronavirus (2019-nCoV) infection has prompted a precautionary approach from Australian medical authorities but most people with the virus are experiencing mild disease according to the World Health Organization. However...
The outbreak of the 2019 novel coronavirus (2019-nCoV) infection has prompted a precautionary approach from Australian medical authorities...
Childhood pneumonia and pleurisy lead to smaller lungs: Tasmanian study
Episodes of childhood pneumonia or pleurisy by age seven are associated with modestly smaller lung volumes in middle age, according to new research. The research, from the Tasmanian Longitudinal Health Study cohort, involved comprehensive measures of lung function in participants...
Episodes of childhood pneumonia or pleurisy by age seven are associated with modestly smaller lung volumes in middle age, according...
TB rates drop with active screening
Australian funded and supported research in Vietnam has demonstrated that active community-wide screening can substantially reduce the prevalence of tuberculosis in areas with a high burden of disease. The findings, published in the New England Journal of Medicine, support the...
Australian funded and supported research in Vietnam has demonstrated that active community-wide screening can substantially reduce the prevalence of tuberculosis...
miRNA can predict CAP complications
Quick and inexpensive microRNA analyses may be able to help predict severe complications in patients hospitalised with community acquired pneumonia (CAP). The 2019 ERS Congress was told specific miRNAs were associated with different pneumonia endotypes and could help differentiate which patients...
Quick and inexpensive microRNA analyses may be able to help predict severe complications in patients hospitalised with community acquired pneumonia...
Early wins in lab for inhaled TB vaccine
Australian researchers have developed a novel synthetic lipopeptide conjugate vaccine delivered via inhalation to the pulmonary mucosa that increased immunogenicity and efficacy against tuberculosis (TB) in a pre-clinical model. As reported in the Journal of Medicinal Chemistry, the experimental vaccine...
Australian researchers have developed a novel synthetic lipopeptide conjugate vaccine delivered via inhalation to the pulmonary mucosa that increased immunogenicity...
Azithromycin reduces rhinovirus replication in airways
Prophylactic treatment with azithromycin mitigates the impact of human rhinovirus infection in lung transplant recipients, Australian research shows. A WA study using large and small airway epithelial cells from five lung allograft recipients has confirmed rhinovirus caused significant cytotoxicity in both...
Prophylactic treatment with azithromycin mitigates the impact of human rhinovirus infection in lung transplant recipients, Australian research shows. A WA study...
Antibiotics prevent asthma exacerbations, but at a cost
There is a clear trade off between the use of macrolides to prevent exacerbations in severe asthma and the likelihood of patients experiencing adverse events such as gastrointestinal symptoms. Dr Chris Cates, co-ordinating editor of the Cochrane Airways Review Group in the...
There is a clear trade off between the use of macrolides to prevent exacerbations in severe asthma and the likelihood...
Flu antivirals may save lives if given early
Oseltamivir appears to be more effective against influenza A/H3N2 in a severely ill population than it is against A/H1N1 or influenza B but early treatment is essential. A Greek study of 1,330 patients admitted to intensive care or mechanically ventilated...
Oseltamivir appears to be more effective against influenza A/H3N2 in a severely ill population than it is against A/H1N1 or...
‘Pulmonary immunisation’ may offer better protection against TB
Australian researchers are a step closer to developing a more effective vaccine against tuberculosis based on a novel ‘pulmonary immunisation’ technique. Scientists at the Centenary Institute in Sydney have demonstrated how an influenza-based vaccine can be used to activate CD4+ memory T...
Australian researchers are a step closer to developing a more effective vaccine against tuberculosis based on a novel ‘pulmonary immunisation’...
Fully oral regimens for MDR-TB should help improve compliance: WHO
A rapid communication issued by the WHO highlights the immediate steps to be taken to ensure that people with multidrug resistant tuberculosis or rifampicin resistant tuberculosis receive treatment in accordance with the latest evidence on effectiveness and safety. “While understanding that it would not...
A rapid communication issued by the WHO highlights the immediate steps to be taken to ensure that people with multidrug resistant...
Machine learning could give early warning of respiratory epidemics
A national surveillance system for respiratory epidemics could use machine learning to analyse real time data and give early warning of emerging events such as thunderstorm asthma, an expert panel has been told. A national workshop of stakeholders convened in...
A national surveillance system for respiratory epidemics could use machine learning to analyse real time data and give early warning...
Hospital apologises for respiratory infection data breach
SA Health has apologised for a data breach in which test results for children with respiratory infections were published on a hospital website. Pathology test results relating to patients treated for respiratory infections such as pertussis at...
SA Health has apologised for a data breach in which test results for children with respiratory infections were...
Immunotherapy against CMV to help organ recipients
Autologous adoptive T-cell therapy has been successfully used to fight recurrent or drug-resistant cytomegalovirus (CMV) infections in recipients of solid organ transplants. The phase 1 clinical trial, led by the QIMR Centre for Immunotherapy and Vaccine Development, treated 13 patients...
Autologous adoptive T-cell therapy has been successfully used to fight recurrent or drug-resistant cytomegalovirus (CMV) infections in recipients of solid...
Dr Noel Bayley recognised with AM for humanitarian work
He is a cardiology and respiratory medicine physician who has helped save the lives of dozens of young people with rheumatic heart disease (RHD) living in Timor Leste. Last week Victorian physician Dr Noel Bayley was honoured for his humanitarian work...
He is a cardiology and respiratory medicine physician who has helped save the lives of dozens of young people with...
Gene sequencing gives early warning on drug resistance in TB
Computer simulation of 3D protein structures associated with gene mutations in Mycobacterium tuberculosis has been used to predict resistance to pyrazinamide in tuberculosis treatment. The technology can be used to ‘pre-emptively identify likely resistance mutations in drug targets’ rather than waiting...
Computer simulation of 3D protein structures associated with gene mutations in Mycobacterium tuberculosis has been used to predict resistance to...
Phage therapy makes a comeback to counteract multidrug resistance
Dr Thomas Patterson’s wife was told to expect the worst after he contracted a multidrug resistant Acinebacter baumannii infection in Egypt in 2015. Despite being flown to Germany for treatment and eventually home to the US, he had developed an uncontrolled intra-abdominal...
Dr Thomas Patterson’s wife was told to expect the worst after he contracted a multidrug resistant Acinebacter baumannii infection in Egypt...
Direct acting antivirals expand organ donation
A surge in deaths from the opioid crisis in North America has expanded the potential pool of relatively young organ donors with excellent lung function - if transplant centres are prepared to use hepatitis C positive donors. Dr Marie Budev, from...
A surge in deaths from the opioid crisis in North America has expanded the potential pool of relatively young organ...
Sneezes on a plane: study shows in-flight respiratory infection transmission risk
An airline passenger with influenza or other respiratory infection will not transmit infection to passengers seated more than two seats away laterally or one row in front or back, US research...
An airline passenger with influenza or other respiratory infection will not...
1 in 6 cases of whooping cough are caused by this ‘hidden’ respiratory pathogen
A pathogen similar to Bordetella pertussis is responsible for as many one in six cases of whooping cough, Australian infectious disease specialists have confirmed. Bordetella holmesii causes a respiratory infection similar to...
A pathogen similar to Bordetella pertussis is responsible for as many...
Timing is everything: study shows pre-op physiotherapy beats post-op
A single, 30 minute physiotherapy session delivered before major abdominal surgery can halve the risk of postoperative pulmonary complications including pneumonia. A randomised controlled trial comprising 441 adults across three hospitals in Australia and New Zealand tested the addition of...
A single, 30 minute physiotherapy session delivered before major abdominal surgery can halve the risk of postoperative pulmonary complications including...
Call for vaccination as influenza confirmed as acute MI trigger
It’s been suspected as a trigger for heart attack for many years, but it has taken until now for researchers to confirm that influenza infection is linked to acute myocardial infraction . In a case control study involving 364 cases...
It’s been suspected as a trigger for heart attack for many years, but it has taken until now for researchers...
Why macrolides are a must for CAP
There is now overwhelming evidence to add macrolides to beta-lactams in empiric treatment of community acquired pneumonia (CAP), an Australian respiratory physician says. Despite controversy over the use of macrolides in CAP...
There is now overwhelming evidence to add macrolides to beta-lactams in...
Case detection of TB can be improved
Australian-led research has demonstrated that active case finding in household contacts of people with tuberculosis is more effective than the standard practice of waiting for family members to seek help for their symptoms. Part of the risk with standard practice is...
Australian-led research has demonstrated that active case finding in household contacts of people with tuberculosis is more effective than the...
UK moves to whole genome sequencing for identifying TB strains
England will be the first country in the world to conduct whole genome sequencing (WGS) on all tuberculosis (TB) samples in 2018, delegates attending the BTS Winter meeting have heard. In January, the London-based national mycobacterium reference service (NMRS) laboratory will...
England will be the first country in the world to conduct whole genome sequencing (WGS) on all tuberculosis (TB) samples...
Serious lung infections could be post-vax serotype replacement disease
A leading paediatric respiratory physician has called for enhanced surveillance to determine the impact of the 13-valent pneumococcal vaccine following preliminary data suggesting it might cause an increase in more virulent S. pneumoniae serotypes. Speaking ahead of the Asian Pacific Society...
A leading paediatric respiratory physician has called for enhanced surveillance to determine the impact of the 13-valent pneumococcal vaccine following...
Respiratory and ID specialist turf war stalling antibiotic stewardship
A rift between respiratory physicians and infectious diseases specialists could be stalling efforts to fight the growing problem of antimicrobial resistance in patients with respiratory infections, researchers claim. The study led by infectious disease specialist Associate Professor Jennifer Broome from the...
A rift between respiratory physicians and infectious diseases specialists could be stalling efforts to fight the growing problem of antimicrobial...
Researchers track the origin of Burkholderia pseudomallei
The Burkholderia pseudomallei organism that causes the infectious tropical disease meliodosis originated in Australia before being introduced to Southeast Asia, with subsequent spread to Africa and the Americas, international research has revealed. The researchers led by the UK’s Wellcome Trust Sanger...
The Burkholderia pseudomallei organism that causes the infectious tropical disease meliodosis originated in Australia before being introduced to Southeast Asia,...
Apply caution to latest vitamin D study
Experts have thrown cold water over the findings of a recent meta-analysis that concluded the prevention of acute respiratory tract infection was a “major new indication" for vitamin D supplementation. Writing in an editorial in The BMJ Associate Professor Mark Bolland...
Experts have thrown cold water over the findings of a recent meta-analysis that concluded the prevention of acute respiratory tract infection...
Researchers discover new mechanism of infection for TB
Mycrobacterium tuberculosis infects the body through a previously unknown route of entry, new research suggests. The authors of the mouse study published in Cell Reports say their findings could have significant implications for the development of new therapies to prevent tuberculosis...
Mycrobacterium tuberculosis infects the body through a previously unknown route of entry, new research suggests. The authors of the mouse study...
Perth melioidosis outbreak linked to contaminated saline
Continued use of a bottle of saline to irrigate wounds for at least three months after opening it has been linked to six cases of melioidosis in suburban Perth. This rare infection, caused by Burkholderia pseudomallei, is usually restricted to tropics...
Continued use of a bottle of saline to irrigate wounds for at least three months after opening it has been...
The fight against TB shifts to fixing the immune system, not only bacteria
Tuberculosis (TB) has managed to remain a major global health problem, despite 100 years of research and more than 50 years of treatment being available. It still claims up to...
Tuberculosis (TB) has managed to remain a major global health...
Australian experience of amikacin in NTM disease
Amikacin causes little toxicity in carefully selected and closely monitored patients with non-tuberculous mycobacterial (NTM) disease but is less effective than previously thought, according to a case series published by Brisbane respiratory physicians. Dr Claire Ellender, from the Princess Alexandra Hospital,...
Amikacin causes little toxicity in carefully selected and closely monitored patients with non-tuberculous mycobacterial (NTM) disease but is less effective...
Government to tackle antibiotic apocalypse
The Australian Government has launched a new national strategy aimed at reducing the threat of antibiotic resistance. The National Antimicrobial Resistance Strategy 2015-2019 comes on the back of the new statistics showing Australia’s consumption of antibiotics is among the...
The Australian Government has launched a new national strategy aimed at reducing the threat of antibiotic resistance. The ...
TB and COPD ‘intimately’ connected
Tuberculosis is strongly linked to COPD an Australian review finds, calling into question the belief that people who recover from the disease do not have longer-term problems. Adults over the age of 40 with tuberculosis (TB) were three times more...
Tuberculosis is strongly linked to COPD an Australian review finds, calling into question the belief that people who recover...
Gram-negative resistance a “pressing” concern: experts
Multidrug-resistant gram-negative bacilli is a pressing contemporary concern, compounded by the paucity of new antibiotics say infectious disease experts. In a clinical focus article in the MJA the experts from the University of Queensland and Monash Health in Victoria explain...
Multidrug-resistant gram-negative bacilli is a pressing contemporary concern, compounded by the paucity of new antibiotics say infectious disease experts. In a...
Filming ferrets best for tracking flu
Ferrets used to track the pathogenesis of flu should be monitored by video, influenza researchers from Melbourne say. The method eliminates the limitations of manual scoring, where a 'blind' observer needs to recognise the normal behaviour of ferrets, the researchers led...
Ferrets used to track the pathogenesis of flu should be monitored by video, influenza researchers from Melbourne say. The method eliminates...
13 respiratory conditions on Cochrane priority list
Acute respiratory and airways conditions have made it onto the Cochrane priority list of topics to review 13 times. Published for the first time, Cochrane says the list sets out topics that 'best meet the needs of healthcare and health policy decision...
Acute respiratory and airways conditions have made it onto the Cochrane priority list of topics to review 13 times. Published for the...