respiratory

Quinine risks greater than benefit for leg discomfort

Long-term quinine use for idiopathic leg cramps or restless leg syndrome is associated with an increased mortality risk. The UK findings, published in a JAMA Research Letter, support previous warnings about the off-label use of quinine. The US Food and Drug Administration (FDA) has repeatedly warned about the risks of quinine including life-threatening hypersensitivity reactions, ...

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