New therapy breaks down fibrotic barrier around solid tumours

Australian researchers have developed a therapy that breaks down the fibrous barrier surrounding solid tumours and enhances delivery of anti-cancer drugs to tumour cells. Perth scientists have shown that the extracellular matrix (ECM) targeting peptide, CSG, can be used as a ligand to target TNFα into the thick scaffold of collagen glycoproteins and glycosaminoglycans that ...

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