Patients with advanced melanoma have a new subsidised immunotherapy option following the addition of relatlimab and nivolumab (Opdualag) on the PBS.
The 1 February 2024 listing, which follows a positive recommendation from the Pharmaceutical Benefits Advisory Committee last July, has already been endorsed by Melanoma Institute Australia co-medical director Professor Georgina Long.
Eligibility is expected to include about 940 patients annually with unresectable Stage III or Stage IV malignant melanoma who have not received prior treatment with ipilimumab or a PD-1.
Other criteria include:
- Patient must be at least 12 years of age and weigh 40kg or more,
- Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1,
- Not have uveal melanoma.
Finally, the patient must not have experienced disease progression whilst on adjuvant PD-1 inhibitor treatment or disease recurrence within 6 months of completion of adjuvant PD-1 inhibitor treatment if treated for resected Stage IIIB, IIIC, IIID or IV melanoma, the PBS criteria state.
In a statement for the MIA, Professor Long said the listing was an important development but more needed to be done.