Childhood Cancers

Chemo in childhood linked to higher risk of subsequent malignancies

Chemotherapy, especially higher cumulative doses of the platinum and alkylating agents, is associated with an increased risk of subsequent malignancies in survivors of childhood cancer. A 30-year follow-up of more than 22,000 participants in the Childhood Cancer Survivor Study compared outcomes in patients treated with chemotherapy alone, chemo plus radiotherapy, radiotherapy alone or neither therapy. ...

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