Chemo in childhood linked to higher risk of subsequent malignancies
By Mardi Chapman
6 Nov 2019
Chemotherapy, especially higher cumulative doses of the platinum and alkylating agents, is associated with an increased risk of subsequent malignancies in survivors of childhood cancer. A 30-year follow-up of more than 22,000 participants in the Childhood Cancer Survivor Study compared outcomes in patients treated with chemotherapy alone, chemo plus radiotherapy, radiotherapy alone or neither therapy. ...