Australian study shows antibiotics may have negative effect on checkpoint inhibitor efficacy

Antibiotic use is associated with worse survival in patients with urothelial carcinoma treated with immunotherapy, an Australian study has found Analysis of outcomes for patients involved in two clinical trials – IMvigor210 and IMvigor211 – found that recent antibiotic use (within 30 days) was associated with worse overall survival (hazard ratio 1.44) and progression free ...