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oncology

Lung Cancer

Australian oncologists identify a new biomarker to guide immunotherapy in NSCLC

By Michael Woodhead

26 Nov 2020

HLA-I homozygosity is linked to poor outcomes with immunotherapy in patients with lung cancer and may have value in guiding treatment decisions, according to WA researchers. A study involving 170 patients with advanced NSCLC showed that homozygosity at one or more HLA-I loci was associated with poor survival outcomes with anti-PD1 or anti-PDL1 therapy. The ...

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