Childhood Cancers

Antioxidant prevents cisplatin-induced hearing loss in children

The severe irreversible hearing loss experienced by child cancer patients treated with platinum-based therapies such as cisplatin may be prevented with sodium thiosulphate, according to an international trial involving Australian oncologists. Published in the NEJM, a trial in 12 centres randomised children with liver cancer to be treated with cisplatin plus sodium thiosulfate (57 children) or ...

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