Australians living with many autoimmune and inflammatory diseases will have easier access to affordable rituximab, with the easing of PBS criteria from 1 September.
The listing change to unrestricted benefit opens up access to the monoclonal antibody biologic for patients living with rare conditions such as ANCA vasculitis, neuromyelitis optica and pemphigus vulgaris, as well as immune thrombocytopenic purpura.
The change on September 1 means rituximab now moves from “authority required” listing to “unrestricted benefit” within the S100 highly specialised drugs program. It was recommended by the Pharmaceutical Benefits Advisory Committee last September.
“The PBAC considered that changing the rituximab listings to unrestricted would provide subsidised access to treatment for patients with conditions where there are no alternative PBS listed medicines,” the PBAC found. “The PBAC considered the expanded use would be cost effective given the price reductions to rituximab to date.”
Clinical immunologist Dr Daman Langguth said rituximab could be used for a wide range of applications.
“There are a huge number of conditions,” he said. “This is kind of a first as it is not a drug that is just used by one specialty. This is a game-changer for patients.”
Dr Langguth, head of immunology at Sullivan Nicolaides Pathology in Brisbane, said rituximab would likely be prescribed by rheumatologists as well as haematologists, neurologists, immunologists and dermatologists.
One of the leading voices calling for the expansion of its use under the PBS, Dr Langguth also credited a group letter from patient members of the Australian and New Zealand vasculitis society and the Australasian Society of Clinical Immunology and Allergy and the Australian Rheumatologists Association, for advocating for the change.
“This was doctors and patients getting together to change funding in Australia for rare diseases,” he said.
From today the Australian govt PBS has funded rituximab for all indications if ordered by a specialist: so glad to have been instrumental in this : how cool is this ?
— I am Immune (@DamanLangguth) September 1, 2022