Treating paediatric migraine is not just about using lower adults doses: CHAMP study

Children and adolescents with longstanding migraine experience meaningful improvements in headache status for up to three years after treatment in the Childhood and Adolescent Migraine Prevention (CHAMP) trial. The CHAMP trial which compared amitriptyline, topiramate and placebo in 8-17 year olds with migraine was stopped early due to futility. It found neither of the two ...

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