No clear winners but two drugs stand out for idiopathic neuropathic pain

Nortriptyline and duloxetine are the best, but not great options for managing patients with cryptogenic sensory polyneuropathy (CSPN). A US study of 402 patients from 40 clinical sites comparing nortriptyline, duloxetine, pregabalin and mexiletine found there was a need for new, more effective drugs for idiopathic neuropathic pain. The PAIN-CONTRoLS study, published in JAMA Neurology, ...

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