Botox wear-off effect means headache for some migraine patients

Patients managed with onabotulinumtoxinA (Botox) for their chronic migraine can experience a wear-off in effect before the next scheduled treatment, an international study has found. The retrospective chart review of 112 patients from treatment centres in six countries including Australia found overall headache days significantly increased in weeks 12 and 13 after injection compared to ...

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