Warfarin may worsen OA progression due to VKA effect: study

Warfarin’s vitamin K antagonism may have detrimental effects on joint tissues that could contribute to progression of osteoarthritis, new research suggests. In patients with osteoarthritis receiving anticoagulation for atrial fibrillation, warfarin use was associated with an increased risk of knee and hip replacement – a marker for later stage OA – compared to treatment with ...

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