The indirect benefit of granulocyte-colony stimulating factor (G-CSF) in supporting patients on chemotherapy may be masking its ‘dark side’ – the potential to promote tumour progression and metastasis. A review of the pre-clinical data on G-CSF provides strong evidence that the cytokine can stimulate tumour cell proliferation and promote angiogenesis. G-CSF has also been implicated ...
Time to look closer at the ‘dark side’ of G-CSF
By Mardi Chapman
11 Jul 2018