Blood cancers

Dr Edward Chew: identifying the genes responsible for poor AML outcomes

Dr Edward Chew is a clinical haematologist at the Royal Melbourne Hospital and a PhD candidate at the Walter and Eliza Hall Institute of Medical Research. He recently received a Royal College of Pathologists of Australasia (RCPA) Foundation Illumina Cancer Research Grant to pursue his work on relapse in Acute Myeloid Leukaemia (AML).

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Challenge: can you describe the aim of this project in 10 words? Our aim is to understand how AML can become resistant to chemotherapy and return with a vengeance. Why are you focusing on core-binding factor AML? In general, outcomes in AMLs are poor. The dogma is that core-binding factor AMLs respond well to initial ...

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