Blood cancers

Curing acute promyelocytic leukaemia: ‘Blunderbuss, vitamins, and a poison chaser’

Professor Harry Iland, from Royal Prince Alfred Hospital in Sydney, told the HAA meeting how the treatment of acute promyelocytic leukaemia (APL) has evolved from non-selective ‘blunderbuss’ therapy anthracyclines through the addition of vitamin A-based retinoids and most recently, arsenic. Delivering the Carl de Gruchy Oration, Professor Iland explained how the cytogenetic and molecular abnormalities ...

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