haematology
Coagulation

Andexanet proven effective as an antidote to factor Xa inhibitors

Early experience with andexanet alfa in patients experiencing a serious bleed on rivaroxaban, apixaban or enoxaparin has shown it effectively inhibits the anti-factor Xa drugs and is associated with clinical haemostasis. Presented at the ESC congress in Rome and published simultaneously in the New England Journal of Medicine the ongoing ANNEXA-4 study enrolled patients who had ...

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