Ischaemic heart disease

Arthritis drug fails in inflammation in CVD

Methotrexate has no role in the secondary prevention of atherothrombotic events in patients with a history of myocardial infarction or coronary artery disease. Results from the Cardiovascular Inflammation Reduction Trial (CIRT) of low-dose methotrexate versus placebo in almost 5,000 patients found no impact on laboratory measures of inflammation or clinical end points. Patients also had ...

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