A patient in Victoria has died from a gram-negative infection that was resistant to all antibiotics.
Clinicians from St Vincent’s Hospital and the Royal Melbourne Hospital reported the case of a 59-year-old man from Victoria died from severe sepsis after becoming infected with carbapenemase-resistant Klebsiella pneumonia (CR-KP).
He was admitted to the hospital with severe acute pancreatitis secondary to gallstones and concurrent nosocomial pneumonia.
Doctors initially treated the patient with ceftriaxone, but the patient deteriorated and treatment was switched to piperacillin-tazobactam and then meropenem.
Diagnostic microbiology did not reveal any significant pathogens.
But a pancreatic debridement revealed carbapenem-resistant Klebsiella pneumonia in the pancreatic tissue and the patient was prescribed gentamicin, doxycline, meropenem, ertapenem and fluconazole.