Rheumatoid arthritis

Vaccinate for pneumonia before starting tofacitinib

Response to pneumococcal vaccine may be diminished in patients taking the JAK inhibitor tofacitinib, especially if they are on methotrexate. In two studies researchers from Portland found that tofacitinib diminished PPSV-23 immunogenicity to a similar extent as methotrexate, particularly when the drugs were taken together. Writing in the Annals of the Rheumatic Diseases they say ...

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