Time to soften stance against allopurinol and renal function?

Overcautious use of allopurinol due to misplaced fears it is detrimental to kidney function may be contributing to poor management of gout, research suggests. Contrary to current guidelines on use of the urate-lowering therapy, the use of higher doses (300mg per day) of allopurinol was not associated with renal function deterioration and was in fact ...

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