OA progression may be hastened by warfarin due to VKA effect: study

Warfarin’s vitamin K antagonism may have detrimental effects on joint tissues that could contribute to OA progression, new research suggests In patients with osteoarthritis receiving anticoagulation for atrial fibrillation, warfarin use was associated with an increased risk of knee and hip replacement – a marker for later stage OA – compared to treatment with a ...

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