Biologic infection risk defined in Lancet meta-analysis

Evidence for the risk of serious infection with biologics has been conflicting but the Lancet has just published the most comprehensive meta-analysis of randomised trials to date. The analysis of data from 42330 patients with rheumatoid arthritis from 106 randomised trials found that compared with traditional DMARDS standard-dose biological drugs (OR 1·31) and high-dose biological ...

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