Rare diseases

Maintain a high index of clinical suspicion for AAV in patients with SSc: experts 

The combined pathologies of systemic sclerosis (SSc) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) can result in “potentially devastating” outcomes, according to experts. Though relatively rare, they recommend a vigorous focus on definition and therapeutic strategy for SSc-AAV. AAVs – including granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis – are characterised by ...

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