Knee OA not a monotonic disorder of hyaline cartilage

Inflammation, meniscal damage and bone marrow lesions are the most influential factors in the pathogenesis of knee OA, a large MRI study shows. Using data from the ongoing Osteoarthritis Initiative (OAI) study of 4796 individuals with or at high risk of knee OA the researchers found that only indicators of inflammation and meniscal tear associated significantly ...

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