rheumatology
Public Health

Intervertebral discs have circadian clocks

Disturbed circadian rhythms during normal ageing or in shift workers may contribute to degeneration of intervertebral discs and low back pain, new research suggests. A team from Manchester, UK, identified clear circadian rhythms in mouse disc material and human disc cells. They found a total of 607 genes with 24-hour cycles of expression, representing several ...

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