‘Weak’ opioid agonist’ tramadol linked to increased mortality in OA patients

Prescribing of tramadol in patients with osteoarthritis is associated with a doubled mortality rate compared to patients prescribed NSAIDs, a UK study shows. The increased mortality rate for tramadol was similar to that seen for codeine for which tramadol is often seen as a safer alternative analgesic. The study, published in JAMA, compared all-cause mortality ...

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