Bone health

Denosumab rebound fractures may occur soon after stopping

Vigilance is needed for withdrawal fractures in patients given denosumab, according to South Australian endocrinologists whose patient experienced multiple early rebound fractures including some at non-vertebral sites. Dr Sunita De Sousa of the Endocrine and Metabolic Unit, Royal Adelaide Hospital, reports the case of a  70-year-old woman with postmenopausal osteoporosis who had nine vertebral and rib ...

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