The use of adaptive servo-ventilation to treat central sleep apnoea in patients with systolic heart failure increases mortality, an international trial finds. The randomised SERVE-HF phase III study of 1325 patients with symptomatic chronic heart failure, reduced ejection fraction and central sleep apnoea found that adding adaptive servo-ventilation (ASV) to guideline-based medical treatment did not improve patient outcomes. ...
Plot thickens on sleep disordered breathing and heart failure
23 Sep 2015