Plot thickens on sleep disordered breathing and heart failure

The use of adaptive servo-ventilation to treat central sleep apnoea in patients with systolic heart failure increases mortality, an international trial finds. The randomised SERVE-HF phase III study of 1325 patients with symptomatic chronic heart failure, reduced ejection fraction and central sleep apnoea found that adding adaptive servo-ventilation (ASV) to guideline-based medical treatment did not improve patient outcomes. ...

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