High dose, low impact: why we need to rethink ICS asthma strategy

Escalating doses of inhaled corticosteroids in an effort to head off impending asthma exacerbations is unsuccessful in children and of limited value in adults. US research showed increasing the regular dose of inhaled steroids by a factor of five at the first signs of deterioration in children did not prevent severe asthma exacerbations requiring systemic ...

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