An international study led by Queensland researchers has examined hundreds of BRCA1 and BRCA2 pathogenic and benign variants to isolate those that have most clinical relevance. The study, led by scientists at the QIMR Berghofer Medical Research Institute, Brisbane, collated research and clinical data in a multifactorial likelihood analysis of 1395 BRCA1/2 predominantly intronic and missense variants. It discovered that ...
BRCA variant study sorts out the wheat from the chaff
25 Jun 2019