WAKE-UP: more certainty with thrombolysis in lacunar stroke

Intravenous alteplase appears to be as effective in patients with lacunar stroke as it is in patients with nonlacunar stroke. A post hoc analysis of the WAKE-UP trial data (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke), found 108 of the 503 patients (21.5%) had a lesion consistent with lacunar infarct on MRI. Of ...

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