3 anticonvulsants compared in refractory status epilepticus

There is no difference in effectiveness and safety between three medications commonly used to treat benzodiazepine-refractory status epilepticus, a US randomised controlled trial has found. Fosphenytoin, valproate, and levetiracetam were all effective in about half the patients who had status epilepticus that was unresponsive to treatment with benzodiazepines, according to findings published in the NEJM. ...

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