Uncertainty regarding the effect of levodopa on the progression of early Parkinson’s disease has been resolved with a trial showing the drug has no disease-modifying effect – positive or negative – and should be used as indicated for the management of symptoms. A trial of an early- versus late-start for levodopa therapy published in the NEJM ...
LEAP trial answers question of whether levodopa promotes progression of PD
By Mardi Chapman
6 Feb 2019