neurology
Movement disorders

LEAP trial answers question of whether levodopa promotes progression of PD


Uncertainty regarding the effect of levodopa on the progression of early Parkinson’s disease has been resolved with a trial showing the drug has no disease-modifying effect  – positive or negative – and should be used as indicated for the management of symptoms. A trial of an early- versus late-start for levodopa therapy published in the NEJM ...

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