In brief: Alteplase dosing questions answered; What’s your experience of cannabis in Parkinson’s?; Kids head injury guidelines

Alteplase dosing questions answered Low-dose alteplase (0.6mg/kg) does not appear to provide any additional benefit or harm when compared to standard-dose alteplase (0.9 mg/kg) in the management of patients with lacunar acute ischaemic stroke (AIS). A post-hoc analysis of the ENCHANTED trial has shown patients with definite or probable lacunar AIS have better 90-day functional ...

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