Statin effects on thrombin generation show promise for VTE prophylaxis

Statins reduce thrombin generation in patients with venous thromboembolism (VTE) and may prevent recurrent VTE without increasing bleeding risk, a new study shows. Investigating a mechanism to explain why statins have antithrombotic effects, Dutch researchers have shown that rosuvastatin use is associated with significant reductions in endogenous thrombin potential (ETP) and peak thrombin. The findings ...

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